A patient is diagnosed with periodontal disease, and the provider orders oral doxycycline (Periostat). The patient asks the purpose of the drug. What is the nurse's response?
a. "It is used because of its anti-inflammatory effects."
b. "It inhibits collagenase to protect connective tissue in the gums."
c. "It reduces bleeding and the pocket depth of oral lesions."
d. "It suppresses bacterial growth in the oral mucosa."
ANS: B
Two tetracyclines are used for periodontal disease. Doxycycline inhibits collagenase, which destroys connective tissue in the gums. It is not used for anti-inflammatory effects. Minocycline is used to reduce bleeding and pocket depth and to inhibit bacterial growth.
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