A current problem in modern medicine is the development of drug resistance mutations. This occurs when a mutation arises in a disease-causing microbe making it resistant to a drug and thus rendering the drug useless in treating a specific disease. Many useful drugs are competitive inhibitors of specific enzymes, and the drug-resistance mutations prevent the binding of the drug. These types of
mutations, in addition to preventing competitive inhibitor binding, can also sometimes reduce the activity of the enzyme. Why is that the case? rev: 01_20_2015_QC_CS-4567
A. Binding to the competitive inhibitor is essential for the function of the enzyme
B. These mutations most likely affect an allosteric site on the enzyme
C. These mutations lower the activation energy of the reaction catalyzed by the enzyme
D. These mutations most likely change the shape of the active site of the enzyme
D
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In addition to the senses of vision, taste, smell, hearing, and touch, we also have a sense called proprioception. It tells us the position of our bodies, based in part on stretch receptors in muscles. Proprioceptors are part of the ______________ nervous system.
A. peripheral B. central C. neuroglial D. motor
The human has __________ sets of autosomal chromosomes. What will be an ideal response?
What are the possible phenotypes of the children if the mother's genotype is IAi for blood type and the
father is IBi? (Use the Punnett square to verify your answer.) a. all AB b. A, B c. A, AB d. A, B, O e. A, B, AB, O
An epidemic of the life-threatening disease, cholera, due to water pollution would probably result in
A. no change in population of the area. B. an immediate increase in the numbers of persons in the lower social castes of the population. C. a decrease in population, which is probably not permanent. D. a slight increase because resistant people will reproduce immediately.