Migraine symptoms are thought to be related to amplification of nociceptive signals in which pathway?
A. Cranial nerve (CN) VII relay to spinal nucleus of thalamus
B. Spinothalamic pathway
C. Trigeminothalamocortical pathway
D. Fasciculus cuneatus relay to medial lemniscus
E. None of the above
ANS: C
Rationale: In migraine, function of the facial nerve (Cranial nerve VII), spinothalamic, and fasciculus cuneatus are normal. Activity in the trigeminothalamocortical pathway is amplified.
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