Folic acid analogs can be toxic to normal cells as well as to cancer cells. Which drug will the nurse administer following the administration of methotrexate to "rescue" the normal cells, causing them to be able to continue replication and devel
1. Leucovorin
2. Iron therapy
3. Immunoglobulin
4. Vitamin B12
Correct Answer: 1
Rationale 1: Leucovorin is given to rescue normal cells during methotrexate administration.
Rationale 2: Iron therapy does not rescue normal cells from folic acid analogs.
Rationale 3: Immunoglobulin does not rescue normal cells from folic acid analogs.
Rationale 4: Vitamin B12 does not rescue normal cells from folic acid analogs.
Global Rationale: Leucovorin, or folinic acid, is a reduced form of folic acid that is able to enter normal cells but not cancer cells. It is given to rescue normal cells during methotrexate administration. The other drugs are not used for this purpose.
You might also like to view...
Which of the following are reasons to involve an interpreter when working with a patient who speaks a different language than the nurse?
1. It is required by law. 2. In order to make an accurate assessment. 3. In order to develop a trusting relationship. 4. An interpreter is likely to provide the intent of the discussion.
A nurse who is discharging a patient is terminating the helping relationship. Which of the following actions might the nurse perform in this phase? Select all that apply
A) making formal introductions B) making a contract regarding the relationship C) providing assistance to achieve goals D) helping patient perform activities of daily living E) examining goals of relationship for achievement F) helping patient establish helping relationship with another nurse
A patient is brought to the emergency department after coming in contact with organophosphate insecticides while at work. The nurse will expect to administer which medication to reverse the toxic effects of this substance?
a. Atropine sulfate b. Diazepam c. Epinephrine d. Flumazenil
Why do clinicians favor the drug donepezil over the drug tacrine in the treatment of Alzheimer's disease?
A. Because tacrine is only used to treat very mild forms of the disease B. Because tacrine produces less intense drugs effects than donepezil C. Because tacrine is associated with more side effects than donepezil D. Because tacrine is an irreversible anticholinesterase inhibitor