The client has had malaria for many years. He asks the nurse why medications might not cure his illness when there are several drugs available. What is the best response by the nurse?

1. "When erythrocytes rupture, the parasites are too numerous for medications to be effective."
2. "Late in the illness, the immune system is too overwhelmed for medications to be effective."
3. "Once the parasite starts multiplying in your liver, medications are usually ineffective."
4. "When cysts occur late in the disease, the parasite is too resistant for medications to be effective."


4
Rationale 1: Erythrocytes rupture early in the course of the illness, and medications are more effective at this stage.
Rationale 2: Late in the illness, medications are often ineffective because the parasites are in cysts, not because the immune system is overwhelmed.
Rationale 3: The parasites begin multiplying in the liver in the earliest stage of the illness when medications are most effective.
Rationale 4: When cysts occur inside the host, the parasite is often resistant to pharmacotherapy.
Global Rationale: When cysts occur inside the host, the parasite is often resistant to pharmacotherapy. Erythrocytes rupture early in the course of the illness, and medications are more effective at this stage. Late in the illness, medications are often ineffective because the parasites are in cysts, not because the immune system is overwhelmed. The parasites begin multiplying in the liver in the earliest stage of the illness when medications are most effective.

Nursing

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