A patient has a deficiency of an enzyme that prepares a specific drug for elimination. When planning care for this patient, the nurse remains alert for which response or issue?

a. Toxic blood levels of the drug are more likely to occur.
b. Higher drug dosages will be needed for the intended action to occur.
c. The drug will be eliminated more rapidly in the feces rather than in the urine.
d. Delivery of this drug by the parenteral route is more effective than by the enteral route.


A
When a patient has a deficiency of the enzyme needed for drug elimination, the drug remains in the body much longer. The risk for even "normal" dosages to cause serious side effects is higher, and toxic drug blood levels can occur quickly. If such a drug is prescribed for this patient, the dosage is lowered and the drug is administered less often.

Nursing

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