Nurses should be aware of the strengths and limitations of various biochemical assessments during pregnancy, including that:
a. Chorionic villus sampling (CVS) is becoming more popular because it provides early diagnosis.
b. Maternal serum alpha-fetoprotein (MSAFP) screening is recommended only for women at risk for neural tube defects.
c. Percutaneous umbilical blood sampling (PUBS) is one of the triple-marker tests for Down syndrome.
d. MSAFP is a screening tool only; it identifies candidates for more definitive procedures.
ANS: D
MSAFP is a screening tool, not a diagnostic tool. CVS provides a rapid result, but it is declining in popularity because of advances in noninvasive screening techniques. MSAFP screening is recommended for all pregnant women. MSAFP screening, not PUBS, is part of the triple-marker tests for Down syndrome.
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