Throughout the early decades of the 1900s, the clinical use of cannabis waned. Which of the following explains the loss of the plant’s appeal amongst physicians in Britain and America?
a. The composition of the plant material varied so widely across samples that dosing standardization was essentially impossible.
b. Due to a lack of plant consistency, physicians could never be certain of treatment efficacy.
c. The shelf-life of cannabis was too short and unpredictable.
d. The emergence of pure opioids and synthetic drugs with greater sedating and analgesic actions offered reliable medical alternatives.
e. All of the above reasons contributed to physicians’ loss of admiration for the medical use of cannabis.
Answer: E
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