Which of the following medications is most likely to be given during the initial phase of increased intracranial pressure to shrink brain volume?

a. mannitol (Osmitrol) c. nimodipine (Nimotop)
b. magnesium sulfate d. pyridostigmine bromide (Mestinon)


A

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A Correct. Mannitol (Osmitrol), a potent diuretic, is most likely to be given during the initial phase of increased intracranial pressure to shrink brain volume.
B Incorrect. Magnesium sulfate will not be given during the initial phase of increased intracranial pressure to shrink brain volume. Magnesium sulfate is used to prevent and treat hypomagnesemia, to manage seizures and hypertension, and as a bronchodilator.
C Incorrect. Nimodipine (Nimotop) will not be given during the initial phase of increased intracranial pressure to shrink brain volume. Nimodipine is a calcium channel blocker used to improve neurological deficits due to spasm following subarachnoid hemorrhage.
D Incorrect. Pyridostigmine bromide (Mestinon) will not be given during the initial phase of increased intracranial pressure to shrink brain volume. Pyridostigmine bromide is used to treat myasthenia gravis.

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