DNA helicase inhibitors are well studied as potential drug targets. What would you expect to see if DNA helicase activity is inhibited?
A) The replisome complex would not assemble on the oriC region.
B) The DNA cannot bend, so hydrogen bonds in the 13-mer region of oriC remain intact.
C) Helicase catalyzes ATP hydrolysis and DNA strands separation, so the helix cannot be unwound and strands will not separate.
D) Helicase carries the SSB protein to the open region of DNA, so hydrolysis and strand separation will not occur.
E) Helicase prevents reannealing of the separated strands, so strands would quickly reanneal and DNA replication cannot proceed.
C
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If an organism has five pairs of chromosomes, how many chromosomal combinations are possible at metaphase I of meiosis?
A. 52 B. 105 C. 510 D. 25 E. None of the answers are correct
Compared to white muscle fibers, red muscle fibers ____
a. have fewer mitochondria b. have less myoglobin c. make more ATP by lactate fermentation d. fatigue less easily e. get most of their ATP from creatine phosphate
Which of the following hormones is different from the others based upon the extent of its target cells?
a. corticotropin b. luteinizing hormone c. somatotropin d. thyrotropin e. follicle-stimulating hormone
Two identical ___________ cells are formed. Each cell has received a complete set of chromsomes. The DNA in each chromosome unwinds into a long thin thread so that genes can become active and give the instructions for making proteins.
Fill in the blank(s) with the appropriate word(s).