Development of a chancre is a sign of which sexually transmitted disease?
a. Herpes
b. Syphilis
c. Gonorrhea
d. Chlamydia
ANS: B
The primary stage of syphilis begins with the entry of the Treponema pallidum spirochete through the skin or mucous membranes. Between 3 and 90 days later, a papule develops at the site of entry, then sloughs off, leaving a painless, red, ulcerated area called a chancre. Herpes is associated with vesicular skin lesions. Gonorrhea and Chlamydia are not associated with skin lesions.
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