Using the TNM staging classification system, what does a tumor staged as T4N3M2 mean?
a. No evidence of primary tumor, lymph node involvement, or distant metastasis
b. Carcinoma in situ, regional lymph node involvement, and metastasis to one site
c. Enlarging tumor, increasing lymph node involvement, and distant metastasis
d. Enlarging tumor, no lymph node involvement, or distant metastasis
ANS: C
TNM cancer staging classification system T4N3M2 means progressive increase in tumor size and involvement, increasing involvement of regional lymph nodes, and distant metastasis present.
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