A patient who is an opioid addict has undergone detoxification with buprenorphine [Subutex] and has been given a prescription for buprenorphine with naloxone [Suboxone]. The patient asks the nurse why the drug was changed

Which response by the nurse is correct? a. "Suboxone has a lower risk of abuse."
b. "Suboxone has a longer half-life."
c. "Subutex causes more respiratory depres-sion."
d. "Subutex has more buprenorphine."


A
The combination of buprenorphine and naloxone [Suboxone] discourages intravenous abuse, because with IV use, the naloxone precipitates withdrawal; this effect does not occur with sub-lingual dosing [Subutex]. Suboxone does not differ from Subutex in terms of drug half-life. Sub-utex does not cause more respiratory depression and does not contain more buprenorphine.

Nursing

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