The nucleophile of the second step of spliceosome-mediated pre-mRNA splicing is the:

A. 2' hydroxyl of the branch point adenosine.
B. 3' hydroxyl of a free guanine nucleotide.
C. 3' hydroxyl of the 5' splice site exon.
D. 2' hydroxyl of the 3' splice site intron.


C

Biology & Microbiology

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