What has the primary responsibility for sensing and responding to changes in blood levels of CO2?

a. Apneustic centers
b. Central chemoreceptors
c. Peripheral chemoreceptors
d. Pneumotaxic center


ANS: B
Hydrogen ions stimulate highly responsive chemosensitive nerve cells, located bilaterally in the medulla. Nevertheless, these central chemoreceptors are extremely sensitive to CO2 in an indirect fashion. Through the hydrolysis reaction, as CO2 increases there is a greater release of hydrogen ions to which the chemoreceptors respond.

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