The nurse conducts group education for clients with seasonal allergies, and teaches about the role of histamine. The nurse evaluates that the education has been effective when the clients make which statement?
1. "Histamine is inhibited by nonsteroidal anti-inflammatory drugs (NSAIDs).
2. "Histamine dilates the vessels in the nose, so it is congested and stuffy."
3. "Histamine constricts vessels, causing capillaries to become more permeable."
4. "Histamine is primarily stored in phagocyte cells in the skin."
Correct Answer: 2
Rationale 1: Nonsteroidal anti-inflammatory drugs (NSAIDs) inhibit the synthesis of prostaglandins, and do not affect histamine.
Rationale 2: Histamine dilates blood vessels causing capillaries to become more permeable. The affected area may become congested with blood.
Rationale 3: Histamine dilates, not constricts, vessels, causing capillaries to become more permeable.
Rationale 4: Histamine is primarily stored in mast cells, not phagocyte cells.
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