If citrate levels are high in the cell, but ATP levels are low, what do you think will happen in the cell?

A. Glycolysis will be inhibited, but the Citric acid cycle will be functional, allowing it to be utilized to break down acetyl-CoA generated from beta-oxidation.
B. Glycolysis and the Citric acid cycle will both be inhibited, thus under these conditions there will be no mechanism to generate ATP.
C. In the presence of glucose, glycolysis will run to generate energy for the cell, but the Citric acid cycle will be inhibited.
D. The electron transport chain will be inhibited, causing a build-up of NADH and FADH2. This will inhibit the Citric acid cycle, but in the presence of glucose, glycolysis will still run coupled with fermentation to regenerate NAD+.


Answer: A

Biology & Microbiology

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