Which of the following variables can be calculated from measured arterial blood gas values? 1. The partial pressure of oxygen at which hemoglobin is 50% saturated (P50) 2. pH 3. PCO2 4. HCO3– 5. SaO2
a. 1, 3, and 4 c. 1, 4, and 5
b. 2, 4, and 5 d. 2 and 3
ANS: C
The P50 can be derived by using the oxyhemoglobin dissociation curve to look for the PaO2 at 50% hemoglobin saturation. The HCO3– is derived from measurements of pH and PaCO2 by using the Henderson-Hasselbalch equation. The saturation of hemoglobin can be calculated by using an equation empirically derived from the oxyhemoglobin saturation curve. The pH is measured di-rectly by using a Sanz electrode, and the PaO2 is measured directly by using a Clark electrode.
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