T-cell help of B cells will be impaired if the T cells lack CD28 because
A. CD28 is needed to activate class switching by turning on AICD.
B. CD28 is needed to interact with CD40 on the B cell.
C. CD28 is needed to signal through the B-cell receptor.
D. CD28 is needed to signal through the T-cell receptor.
E. Both B and C.
D
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