A patient tells the nurse during the health history that the last time she received penicillin, she experienced anaphylaxis. Which of the following medications should the nurse advise the patient to avoid?
a. Ibuprofen (Motrin)
b. Doxycycline (Vibramycin)
c. Imipenem (Primaxin)
d. Cefoxitin (Mefoxin)
ANS: D
Cephalosporins can be used with minimal concern in patients with a mild penicillin allergy; however, they should not be administered to patients with a history of a severe reaction to penicillin.
Motrin may increase the risk of bleeding, but the greater concern is anaphylaxis.
Benefits associated with doxycycline and imipenem outweigh the risk of anaphylaxis.
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