A.B. is a 55-year-old man who was referred to the urology clinic by his primary care provider (PCP) because

of an elevated prostate-specific antigen (PSA) level. He reports that he has been feeling well and has no
specific complaints.

He had a complete blood count (CBC), basic metabolic panel, urinalysis (UA), lipid
profile, and screening PSA completed the week before when he was seen by his PCP. His CBC, lipid profile,
UA, and blood chemistry findings are all within normal limits. His PSA is elevated at 11.9 ng/mL, and the
prostate is slightly tender on examination.


A.B. wonders whether he has prostate cancer. What can you tell A.B. about his PSA level?
PSA is a glycoprotein produced by prostate cells. It is unique to the prostate and is not produced
anywhere else in the body. Normally, prostate cells leak a small amount of PSA into the bloodstream;
this small amount is what is measured when a PSA is drawn. An enlarged prostate naturally leaks
more PSA and causes an elevated PSA level in the blood. When a prostate cell is damaged, it leaks
more PSA; damage might be caused by infection, inflammation, or cancer. A.B.'s result of 11.9 ng/mL
reflects a moderate elevation. Further testing needs to be done.

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The primary reason heparin cannot be administered orally is that:

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A nurse dorsiflexes a patient's right ankle 90 degrees and then uses a reflex hammer to strike the appropriate tendon. What is the expected response for this deep tendon reflex?

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