A patient's red cells show globular fragmentation, budding, and microspherocytes. To what have the red cells probably been exposed?
a. Heat
b. Chemicals
c. Oxidant drugs
d. Bartonellosis
ANS: A
Patients with third-degree burns over more than 20% of their bodies may have a severe acute hemolytic anemia. Morphologic red cell changes include globular fragmentation, budding, and microspherocytes. These cells are present for about 24 hours after the injury before they are removed from circulation.
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