A client is seen in the emergency department with severe pain related to a sickle cell crisis. What does the nurse understand is occurring with this client?

A) The client has a decreased tolerance of pain related to the chronic nature of the illness.
B) Bone marrow decreases the erythrocyte production causing decrease in hypoxia.
C) Overhydration enlarges the red blood cells.
D) Vascular occlusion in small vessels decreasing blood and oxygen to the tissues.


D
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The person with sickle cell disease repeatedly suffers from two major problems: (1) episodes of sickle cell crisis from vascular occlusion, which develops rapidly under hypoxic conditions, and (2) chronic hemolytic anemia. During a sickle cell crisis, the sickle-shaped cells lodge in small blood vessels, where they block the flow of blood and oxygen to the affected tissue. The vascular occlusion induces severe pain in the ischemic tissue. The client may have increased tolerance for pain due to the chronic nature of the illness. Bone marrow increases the erythrocyte production. Underhydration increases the client's risk of developing a vaso-occlusive crisis.

Nursing

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