Which medications are the first choices of pharmacotherapy for heart failure? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected
1. Beta-adrenergic blockers
2. Phosphodiesterase inhibitors
3. ACE inhibitors
4. Diuretics
5. Alpha blockers
Correct Answer: 3, 4
Rationale 1: Beta-adrenergic blockers are second-choice pharmacotherapy for heart failure.
Rationale 2: Phosphodiesterase inhibitors are second-choice pharmacotherapy for heart failure.
Rationale 3: ACE inhibitors are first-choice pharmacotherapy for heart failure.
Rationale 4: Diuretics are first-choice pharmacotherapy for heart failure.
Rationale 5: Alpha blockers are not first-choice pharmacotherapy for heart failure.
Global Rationale: ACE inhibitors and diuretics are first-choice pharmacotherapy for heart failure. Beta-adrenergic blockers are second-choice pharmacotherapy for heart failure. Phosphodiesterase inhibitors are second-choice pharmacotherapy for heart failure. Alpha blockers are not first-choice pharmacotherapy for heart failure.
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