A client having a myocardial infarction is receiving alteplase (Activase) therapy. Which of the following actions should be carried out by the nurse to monitor for the most frequent adverse effect?

1. Monitor for bleeding.
2. Assess for allergic reaction.
3. Evaluate the client for muscle weakness.
4. Monitor for signs and symptoms of infection.


1

Rationale: Alteplase is a thrombolytic medication, which means that it breaks down or dissolves clots; therefore, bleeding is a concern. Local or systemic infection could occur with poor aseptic technique during medication administration, but it is rare. Allergic reaction is not a frequent response. Muscle weakness is not an adverse effect of this medication.

Nursing

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