Which of the following facts underlies the application of RNA interference in the treatment of disease?
A) Restriction enzymes are able to cleave genetic molecules at predictable sites.
B) It is possible to produce proteins that have therapeutic properties.
C) Faulty gene activity that produces unwanted proteins can sometimes be stopped.
D) Individual differences are attributable to a very small percentage of the genes in the human body.
Ans: C
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RNAi is premised on the fact that several genetic disorders are not due to missing genes, but due to faulty gene activity. RNAi can sometimes be used to stop genes from making unwanted disease proteins. Restriction enzymes underlie gene isolation and cloning. The existence of a haplotype and the ability to produce therapeutic proteins are not central to RNAi.
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