A client is being discharged after a hospital admission for chest pain with a multidrug regimen that includes a new prescription for cholestyramine (Questran)

It is most important for the nurse to include which information in discharge teaching about this drug?
1. "You must carefully follow instructions for mixing this drug with liquid."
2. "If you experience bloating or constipation, you should stop taking this drug."
3. "We will monitor your kidney function while you are taking this drug."
4. "Do not take vitamin supplements while taking cholestyramine."


Correct Answer: 1
Rationale 1: Failure to mix the powdered form of this drug adequately can cause gastrointestinal tract obstruction.
Rationale 2: Gastrointestinal effects such as bloating and constipation are common side effects of cholestyramine. Since this drug binds with many other drugs in the gastrointestinal tract, suddenly stopping the drug could increase absorption of other drugs and lead to drug toxicity.
Rationale 3: Bile acid sequestrants such as cholestyramine are not systemically absorbed, and do not threaten kidney function.
Rationale 4: Cholestyramine can reduce absorption of fat-soluble vitamins, so supplementation with vitamins A and D might be necessary.
Global Rationale: Failure to mix the powdered form of this drug adequately can cause gastrointestinal tract obstruction. Gastrointestinal effects such as bloating and constipation are common side effects of cholestyramine. Since this drug binds with many other drugs in the gastrointestinal tract, suddenly stopping the drug could increase absorption of other drugs and lead to drug toxicity. Bile acid sequestrants such as cholestyramine are not systemically absorbed, and do not threaten kidney function. Cholestyramine can reduce absorption of fat-soluble vitamins, so supplementation with vitamins A and D might be necessary.

Nursing

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