Both Streptococcus pneumoniae and Cryptococcus neoformans are causes of meningitis, and both are diagnosed by microscopic observation. How are they distinguished in the microscope?
A. Because Cryptococcus is a fungus, it will not react in the Gram stain, and the cells will always remain colorless.
B. These organisms have different cellular arrangements; Streptococcus form chains, whereas Cryptococcus forms irregular clusters of cells.
C. Cryptococcus is a fungus whereas Streptococcus is a bacterium; cells will be dramatically different in complexity and size.
D. Streptococcus has a prominent capsule that can be observed by negative staining of the sample.
Answer: C
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