In which situation is it appropriate for the nurse to instruct the client to stop taking minocycline (Minocin) and promptly seek medical advice?
1. The client reports epigastric burning.
2. The client reports dizziness and vertigo.
3. The client reports vaginal discharge.
4. The client reports occasional nausea.
Correct Answer: 2
Rationale 1: Epigastric burning is a common side effect but does not require discontinuation of the drug.
Rationale 2: Minocycline is the only tetracycline that can cause reversible vestibular toxicity. Symptoms include dizziness, vertigo, and weakness.
Rationale 3: Vaginal discharge may be a symptom of a yeast infection and should be evaluated for treatment, but most likely does not require discontinuation of the drug.
Rationale 4: Occasional nausea is a common side effect but does not require discontinuation of the drug.
Global Rationale: Minocycline is the only tetracycline that can cause reversible vestibular toxicity. Symptoms include dizziness, vertigo, and weakness. Occasional nausea and epigastric burning are common side effects but do not require discontinuation of the drug. Vaginal discharge may be a symptom of a yeast infection and should be evaluated for treatment, but most likely does not require discontinuation of the drug.
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