A 67-year-old male was diagnosed with polycythemia vera (PV) but refused treatment. His con-dition is at risk for converting to:
a. chronic lymphocytic leukemia.
b. Burkitt lymphoma.
c. multiple myeloma.
d. acute myeloid leukemia.
ANS: D
A significant potential outcome of PV is the conversion to acute myeloid leukemia (AML), oc-curring spontaneously in 10% of individuals and generally being resistant to conventional thera-py. Neither chronic lymphocytic leukemia, Burkitt lymphoma, nor multiple myeloma is a signifi-cant outcome of PV.
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