The nursing instructor is teaching student nurses about how the median effective dose of a medication is related to clinical practice. Which statement reflects the correct understanding by the student?
1. "About 50% of clients will experience severe side effects from the drug."
2. "About 50% of clients will not experience any effect from the drug."
3. "Some clients will respond differently, depending on their ethnic background."
4. "Some clients will require more or less than the average dose of the drug."
Correct Answer: 4
Rationale 1: The median effective dose does not predict how many clients will experience severe side effects from the drug.
Rationale 2: The median effective dose does not predict that 50% of clients will not experience an effect of the drug.
Rationale 3: The median effective dose is not related to ethnicity.
Rationale 4: The median effective dose is the dose required to produce a specific therapeutic response in 50% of a group of clients.
Global Rationale: The median effective dose is the dose required to produce a specific therapeutic response in 50% of a group of clients. The median effective dose does not predict how many clients will experience severe side effects from the drug. The median effective dose is not related to ethnicity.
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