Briefly explain the formation of bone in the human body

Question

What will be an ideal response?

Answer 1

The fetal skeleton is first made of cartilage. Cartilage is strong and flexible, and the cartilage cells are able to divide and grow as the fetus grows. During the third month of fetal development, osteoblasts begin to form a collar around the long bones in the fetus. The osteoblasts form from cartilage cells that are transformed as blood vessels form around the cartilage. These osteoblast collars support the bones as the cartilage inside breaks down, leaving a cavity inside. The cavity is filled with hollow space that the osteoblast cells fill with spongy bone. The osteoblasts secrete collagen and other organic material, which then mix with calcium salts to form mature bone cells called osteocytes that are unable to divide. The epiphyseal plates form at the end of the long bones, and the long bones are able to grow from these structures.