What are the primary uses of neuromuscular junction blockers (NMJ) blockers? (Select all that apply.)
A) To facilitate endotracheal intubation
B) To sedate patient for general anesthesia
C) To prevent injury during electroconvulsive therapy
D) To provide greater ease in extubating patient
E) To facilitate mechanical ventilation
A, C, E
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NMJ blockers are primarily used as adjuncts to general anesthesia, to facilitate endotracheal intubation, to facilitate mechanical ventilation, and to prevent injury during electroconvulsive therapy. NMJ blockers do not sedate the patient who will be paralyzed after administration but will remain alert unless another medication is given. These medications would not be given before extubation because respiratory muscles would be paralyzed, resulting in the inability to breathe.
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