In systemic lupus erythematosis (called lupus), complexes of antibody and antigen form, and these immune complexes insert themselves into small blood vessels, joints, heart, and kidney, causing damage to the organ tissue. The course of the disease is unpredictable, with periods of illness alternating with remissions. How is lupus, a type III autoimmune disease, similar to the tuberculin reaction, a type IV hypersensitivity reaction?
A. Both lupus and the tuberculin reaction involve large amounts of antibody production.
B. Both lupus and the tuberculin reaction utilize IgE in their mechanisms.
C. Both lupus and the tuberculin reaction are immediate hypersensitivities, occurring within a few hours.
D. The mechanism of both lupus and the tuberculin reaction involve large amounts of inflammatory chemicals released into tissue.
Answer: D
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