A patient who was recently prescribed spironolactone calls the clinic and complains that he is not urinating as much as he did when he first started taking this medication. What would be an appropriate question for the nurse to ask this patient?
A) "Are you taking a salicylate?"
B) "Are you taking acetaminophen?"
C) "Are you taking ibuprofen?"
D) "Are you using a lot of salt?"
A
Feedback:
The diuretic effect decreases if potassium-sparing diuretics are combined with salicylates. Dosage adjustment may be necessary to achieve therapeutic effects. There is no decrease in effect when spironolactone is combined with acetaminophen, ibuprofen, and increased sodium intake.
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