When administering acetylcysteine (Mucomyst), the respiratory therapist should be particularly focused on which of the following potential adverse effects?

1. Incompatibility with certain antibiotics when administered together
2. Blurred vision
3. Bronchospasm
4. Airway obstruction due to rapid liquefaction of mucus
a. 3 only
b. 1, 2, and 3 only
c. 2, 3, and 4 only
d. 1, 3, and 4 only


ANS: D
Other side effects that can occur include the following:
? Airway obstruction due to rapid liquefaction of secretions
? Disagreeable odor due to hydrogen sulfide
? Incompatibility with certain antibiotics (sodium ampicillin, amphotericin B, erythromycin, tet-racyclines, and aminoglycosides) if mixed in solution
? Increased concentration and toxicity of nebulizer solution toward end of treatment
? Nausea and rhinorrhea
? Stomatitis
? Reactivity of acetylcysteine with rubber, copper, iron, and cork

Health Professions

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