Why does a rise in blood pressure tend to cause swelling, especially in the feet? Why does Kwashiorkor (protein deficiency) also cause swelling?
What will be an ideal response?
Answer: Fluid is pushed out of the capillaries into the interstitial fluid by blood pressure; higher blood pressures will tend to push more fluid out of the capillaries, and this fluid tends to accumulate in the feet due to gravity. Fluid can be pulled back into the capillaries by the higher osmotic pressure of plasma relative to interstitial fluid, which is due to the fact that protein levels are higher in the plasma than the interstitial fluid. With Kwashiorkor, protein levels in the blood decline, leading to more fluid in the interstitial compartment (= swelling).
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