Which of the following series of events is associated with the formation of cancer?
A. The oncogenes mutate and become proto-oncogenes which are continuously active. There is also an associated loss of tumor suppressor gene activity allowing uncontrolled growth of cells.
B. The proto-oncogenes mutate and become oncogenes which are continuously active. There is also an associated loss of tumor suppressor gene activity allowing uncontrolled growth of cells.
C. The proto-oncogenes mutate and become oncogenes which stop functioning altogether. There is also an associated increase in the tumor suppressor gene activity allowing uncontrolled growth of cells.
D. The oncogenes mutate and become proto-oncogenes which stop functioning altogether. There is also an associated increase in the tumor suppressor gene activity allowing uncontrolled growth of cells.
Answer: B
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