Which of the following statements is true regarding the Tuskegee Syphilis Study? The
a. proven medical treatment, when available, was withheld from the subjects.
b. purpose of the study outweighed the risks and continued for 40 years.
c. research design was amended so that it could continue regardless of the outcome.
d. subjects did not know they were in a study.
ANS: A
Penicillin, developed in the 1930s and 1940s, was deliberately withheld from the research subjects and their families, so as to study the effects of the natural progression of syphilis.
The purpose of the study, the benefits of the knowledge gained, did not outweigh the risks of untreated disease, not only onto the subjects of the study, but also to the sexual contacts and children of the subjects who also contracted syphilis.
The original research study design was set to continue through the natural progression of the disease.
The subjects were aware that they were in a research study. The problem was that they were not fully informed as to the nature of the study.
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