The nurse, caring for a patient with an infected pressure ulcer, realizes that neutrophils and macrophages will arrive to the wound as a part of the natural body response

The mechanism that signals the neutrophils and macrophages to arrive to the wound is considered 1. chemotaxis.
2. migration.
3. margination.
4. diapedesis.


1

Rationale: Circulating neutrophils and monocytes have to arrive where they are needed and then they must be able to transfer from the blood vessels to the site of injury. This process involves multiple steps which are margination, diapedesis, migration, and chemotaxis. Margination occurs as circulating leukocytes begin to accumulate and adhere to the capillary wall. Once the cells have adhered to the capillary wall, they develop pseudopods and squeeze out of the capillary using ameboid movement, a process called diapedesis. After the leukocyte is outside the capillary, it requires guidance to move to the correct location. This is accomplished through chemotaxis, which refers to movement as a result of some type of chemical stimulus. Migration is not a step in this process.

Nursing

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The nurse discussing organ donation with a family member of a severely brain-injured patient is asked about the signs of brain death. The nurse knows that which of the following diagnostic tests will be done to confirm brain death?

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