A nurse is explaining the difference between an acquired disorder and a genetic disorder to a couple during genetic counseling. Which of the following would the nurse use as examples of genetic diseases? Select all that apply

A) Neurofibromatosis
B) Fetal alcohol syndrome
C) Tay-Sachs disease
D) Neonatal abstinence syndrome
E) Down syndrome
F) Sickle cell disease


A, C, E, F
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A genetic disorder is a physical or mental abnormality resulting from a defect in genetic structure. Neurofibromatosis, Tay-Sachs disease, Down syndrome, and sickle cell disease are all genetic disorders. Many conditions are congenital, but not genetic; they are acquired. Examples of acquired disorders are those that are caused by teratogens, such as alcohol, drugs, maternal diseases, and toxic substances. Fetal alcohol syndrome and neonatal abstinence syndrome are acquired disorders related to the mother's alcohol and drug use, respectively.

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