Calculate the P(A-a)Do2 for a neonate who has the following ABGs while breathing an Fio2 of 0.8 HFV: pH 7.32; PaCO2 55 mm Hg; PaO2 50 mm Hg; 22 mEq/L The inspired gas is 100% humidified at body temperature, and the patient has a normal respiratory quotient
A. 425
B. 450
C. 490
D. 525
ANS: B
A. Incorrect response: See explanation B.
B. Correct response: The alveolar-arterial O2 tension difference is calculated as follows:
STEP 1: Determine the corrected barometric pressure (Pcorrected).
Pcorrected = PB – PH2O
= 760 mm Hg – 47 mm Hg
= 713 mm Hg
STEP 2: Determine the Pio2.
Pio2 = Pcorrected × Fio2
= 713 mm Hg × 0.8
= 570 mm Hg
STEP 3: calculate the P(A-a)Do2.
{Comp: small cap o, io, co, and o in Do2, Pio2, Paco2, Pao2, respsectively}
= 450 mm Hg
C. Incorrect response: See explanation B.
D. Incorrect response: See explanation B.
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