In smooth muscle, cross-bridging occurs due to
A. Ca2+ binding to troponin.
B. Ca2+ binding to calmodulin.
C. both Ca2+ binding to troponin and calmodulin.
D. myosin kinase adding a phosphate to myosin heads.
E. both Ca2+ binding to calmodulin and myosin kinase adding a phosphate to myosin heads.
Answer: E
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