Which couples may benefit from prenatal diagnosis? Note: Credit will be given only if all correct and no incorrect choices are selected. Select all that apply
1. Couples including women under the age of 35
2. Couples with an unbalanced translocation
3. Couples with a family history of known or suspected single-gene disorder
4. Couples including women with a teratogenic risk secondary to an exposure or maternal health condition
5. Family history of birth defects and/or intellectual disability
3, 4, 5
Explanation: 3. Couples with a family history of known or suspected single-gene disorder (e.g., cystic fibrosis, hemophilia A or B, Duchenne muscular dystrophy) may benefit from prenatal diagnosis.
4. Women with a teratogenic risk secondary to an exposure or maternal health condition (e.g., diabetes, seizure disorder) may benefit from prenatal diagnosis.
5. Family history of birth defects and/or intellectual disability (mental retardation) (e.g., neural tube defects, congenital heart disease, cleft lip and/or palate) may benefit from prenatal diagnosis.
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