A child weighing 44 lbs. is prescribed amoxicillin (Amoxil). The recommended amount is 25-50 mg/kg/day provided in q 8 hr or q 12 hr divided doses. What is a safe single dose that should be prescribed for this medication?
1. 500 mg q 8 hr
2. 400 mg q 6 hr
3. 400 mg q 12 hr
4. 600 mg a 12 hr
3
Rationale 1: First, determine the safe dose range for this medication. Mg/day = 25 mg/1 kg x 1 kg/2.2 lbs x 44 lbs = 500 mg/day; mg = 50 mg/1 kg x 1 kg/2.2 lbs x 44 lbs = 1000 mg. The one dose that is within the parameters is 400 mg PO q 12 hours.
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