Ischemia and other toxic injuries increase the accumulation of intracellular calcium as a result of:
A) Release of stored calcium from the mitochondria
B) Improved intracellular volume regulation
C) Decreased influx across the cell membrane
D) Attraction of calcium to fatty infiltrates
Ans: A
Feedback:
Disruption of the normal intracellular functions causes the impaired mitochondria to release stored calcium. Cell injury disrupts intracellular volume regulation, allowing excessive influx of substances across the impaired cell membrane. Fatty infiltrate is an ominous sign of cell damage and does not interact with calcium.
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