A researcher using intracranial self-stimulation (ICSS) to assess the abuse liability of an investigational drug should be most concerned when the investigational drug
a. has a strong capacity to lower the threshold of responding and facilitate the rate of operant responding in rats.
b. has a strong capacity to raise the threshold of responding and facilitate the rate of operant responding in rats.
c. has a strong capacity to lower the threshold of responding and impede the rate of operant responding in rats.
d. has a strong capacity to raise the threshold of responding and impede the rate of operant responding in rats.
e. None of the above—the ICSS paradigm cannot be used to assess the abuse liability of a drug.
Answer: A
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a. ?substantia nigra and sensory neurons b. ?spinal cord, sensory neurons, and motor neurons c. ?cerebral cortex and motor neurons d. ?amygdala and sensory neurons
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a. incubation; mental set c. insight; mental set b. a rest period; functional fixedness d. incubation; functional fixedness
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a. true b. false