A client's oncologist has presented the possibility of implementing biotherapy in the treatment of the client's brain tumor. Which of the following mechanisms of action provide the therapeutic effects of biotherapy? Select all that apply
A) Stimulating the immune response to tumor cells
B) Inhibiting tumor protein synthesis
C) Reversing angiogenesis
D) Altering the hormonal environment of tumor cells
E) Causing breaks in the DNA of tumor cells
Ans: A, B
Feedback:
Biotherapy exerts therapeutic effects by way of altering host responses (such as by stimulating the immune response) or by inhibiting tumor cell biology (e.g., inhibiting protein synthesis). Biotherapy does not reverse existing angiogenesis, and the hormonal environment is not a particular focus of biotherapy. Radiation is the primary means by which breaks in tumor DNA are made.
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