How has synthetic recombinant antihemophilic factor improved the management of hemophilia? (Select all that apply.)
a. Eliminates the need for frequent transfusions
b. Can be administered by family at home
c. Prevents hemorrhage
d. Reduces cost of care of the hemophiliac
e. Reduces risk of HIV and hepatitis A and B transmission
ANS: A, B, D, E
The drug can be given at home by the family. Because it supplies the missing factor, transfusions are not necessary and consequently the exposure to HIV and hepatitis A and B is reduced. Cost of care is greatly reduced because hospitalizations and transfusions are not as frequently required. The drug does not prevent hemorrhage; it makes hemorrhage manageable.
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