A patient involved in a motor vehicle accident was admitted to the intensive care unit with a closed head injury. Which clinical manifestation would warn the nurse that the patient's condition was progressing to multiple organ dysfunction syndrome (MODS)?
1. Urine output less than 400 mL/day
2. Decreased PaO2 with an increase in FiO2
3. Alteration in level of consciousness
4. Hypotension that responds to fluids
Answer: 2
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